| | 91421-42-0 Basic information More.. |
| Product Name: | Rubitecan | | Synonyms: | 9-Nitrocamptothecin (Rubitecan);9-Nitrocamptothecin;RFS 2000;9-Nitrocellulose camptothecine;9-NITRO-CPT;9-NITRO-20(S)-CAMPTOTHECIN;(4s)-4-ethyl-4-hydroxy-10-nitro-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione;RUBETICAN | | CAS: | 91421-42-0 | | MF: | C20H15N3O6 | | MW: | 393.35 | | EINECS: | | | Mol File: | 91421-42-0.mol |  |
Use
Rubitecan, marketed by Supergen as Orathecin, is a promising oral treatment for solid melanoma, prostate, breast, ovarian, and other cancers, as well as leukemia. It is a derivative of camptothecin, a topoisomerase inhibitor known from Chinese Traditional Medicine. It selectively targets the critical S-stage of cellular reproduction particularly in acidic environments, as in many cancer cells relaxing DNA supercoiling and generating lethal breaks in the DNA. Due to insolubility, its biological delivery mechanism is not yet effective, and it has not been approved for clinical use.
- Rubitecan
-
- US $23.00 / kg
- 2022-12-26
- CAS:91421-42-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg
- Rubitecan
-
- US $0.00-0.00 / KG
- 2022-10-14
- CAS:91421-42-0
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1Ton
- Rubitecan USP/EP/BP
-
- US $1.10 / g
- 2021-07-03
- CAS:91421-42-0
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
|
|
91421-42-0
Recommend Suppliers |
|