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| PT-2385 Basic information |
Product Name: | PT-2385 | Synonyms: | PT-2385;CS-2108;PT 2385;PT-2385;Benzonitrile, 3-[[(1S)-2,2-difluoro-2,3-dihydro-1-hydroxy-7-(methylsulfonyl)-1H-inden-4-yl]oxy]-5-fluoro-;(S)-3-(2,2-Difluoro-1-hydroxy-7-methanesulfonyl-indan-4-yloxy)-5-fluoro-benzonitrile;(S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile;Inhibitor,inhibit,Hypoxia-inducible factors,HIF/HIF Prolyl-Hydroxylase,HIF-PH,PT 2385,HIFs,PT-2385,PT2385;(methylsulfonyl) | CAS: | 1672665-49-4 | MF: | C17H12F3NO4S | MW: | 383.34 | EINECS: | | Product Categories: | | Mol File: | 1672665-49-4.mol | |
| PT-2385 Chemical Properties |
Boiling point | 524.7±50.0 °C(Predicted) | density | 1.57±0.1 g/cm3(Predicted) | storage temp. | Sealed in dry,Store in freezer, under -20°C | solubility | DMSO:50.0(Max Conc. mg/mL);130.43(Max Conc. mM) | pka | 11.28±0.40(Predicted) |
| PT-2385 Usage And Synthesis |
Uses | PT2385 is a HIF-2α antagonist with EC50 of 27 nM in the luciferase assay, with no apparent off-target effects. |
| PT-2385 Preparation Products And Raw materials |
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