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| Product Name: | THPP-1 | | Synonyms: | THPP-1;PDE10A,SIMA,object,THPP 1,recognition,Phosphodiesterase (PDE),Inhibitor,inhibit,novel,THPP-1,THPP1;Methanone, [2-(6-chloro-3-pyridinyl)-7,8-dihydro-4-(2-methoxyethoxy)pyrido[4,3-d]pyrimidin-6(5H)-yl]imidazo[1,5-a]pyridin-1-yl- | | CAS: | 1257051-63-0 | | MF: | C23H21ClN6O3 | | MW: | 464.9 | | EINECS: | | | Product Categories: | | | Mol File: | 1257051-63-0.mol |  |
| | THPP-1 Chemical Properties |
| density | 1.45±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 31.25 mg/mL (67.22 mM) | | form | A solid | | pka | 4.70±0.30(Predicted) |
| | THPP-1 Usage And Synthesis |
| Biological Activity | THPP-1, a chemical probe recommended by SGC, is a potent and orally active inhibitor of phosphodiesterase 10A (PDE10A) with Ki values of 1 nM and 1.3 nM for human and rat, respectively. THPP-1 has good pharmacological properties. | | target | |
| | THPP-1 Preparation Products And Raw materials |
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