| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Monoclonal Anti-Cytokeratin, pan (Mixture) antibody produced in mouse
Purity:clone C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, ascites fluid Package:100UL Remarks:C2562-100UL
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Product Name:Monoclonal Anti-pan-Cytokeratin
Purity:clone C-11, ascites fluid Remarks:clone PCK-26, purified immunoglobulin, buffered aqueous solution
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-PAN CYTOKERATIN Basic information |
| Product Name: | ANTI-PAN CYTOKERATIN | | Synonyms: | ANTI-PAN CYTOKERATIN;Monoclonal Anti-Cytokeratin, pan antibody produced in mouse;Monoclonal Anti-Cytokeratin, pan-FITC antibody produced in mouse;Monoclonal Anti-Cytokeratin, pan (mixture);Monoclonal Anti-Cytokeratin, pan (Mixture) Prediluted antibody produced in mouse;Monoclonal Anti-Cytokeratin, pan (Mixture) antibody produced in mouse;MONOCLONAL ANTI-CYTOKERATIN, PAN;MONOCLONAL ANTI-PAN CYTOKERATIN | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-PAN CYTOKERATIN Structure]() |
| | ANTI-PAN CYTOKERATIN Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 21/22-22 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | ANTI-PAN CYTOKERATIN Usage And Synthesis |
| Uses | Monoclonal Anti-Cytokeratin, pan?FITC antibody has been used in immunocytochemistry and has also been used to visualize lung epithelial cells. | | Uses | Monoclonal Anti-Cytokeratin, pan (Mixture) antibody produced in mouse is suitable for the following applications:
- Immunohistochemistry (formalin-fixed, paraffin-embedded sections) using protease-digested sections of human or animal tissues.
- Immunohistochemistry (frozen sections).
- Indirect immunofluorescence (at a working dilution of 1:100 using protease-digested, formalin-fixed, paraffin-embedded sections of human or animal tissues).
- Immunocytochemical labeling (immunofluorescence ) of cells.
- Western blotting.
| | General Description | Monoclonal Anti-Pan Cytokeratin (mouse IgG1 isotype) is derived from the PCK-26 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a cytokeratin preparation from human epidermis. Cytokeratins are a group of at least 29 different proteins. They are characteristic of epithelial and trichocytic cells. Cytokeratin peptide 1 (68 kDa) is expressed together with cytokeratin 10 in the suprabasal cell layers or the differentiation compartment of the epidermis. Its expression increases with epidermal maturation and is modified post translationally in terminally differentiated keratinocytes of the stratum corneum. Cytokeratin peptide 5 (58 kDa) is the primary type II keratin in stratified epithelia, while cytokeratin type 8 (52 kDa) is a major type II keratin in simple epithelia. Cytokeratin 6 (56 kDa) is a "hyperproliferation" cytokeratin expressed in tissues with natural or pathological high turnover. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. | | Biochem/physiol Actions | Cytokeratins helps in subtyping several kinds of epithelial differentiation or for narrowing possible sites of origin for metastatic carcinomas. Cytokeratins may play an important role in transhepatic transport and canalicular secretion. |
| | ANTI-PAN CYTOKERATIN Preparation Products And Raw materials |
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