| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:BBS-4
CAS:402934-09-2
Purity:98% Package:100 mg；5 mg；50 mg
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| Company Name: |
United States Biological
|
| Tel: |
1-800-520-3011 |
| Email: |
sales@advtechind.com |
| Products Intro: |
Product Name:BBS4
|
|
| Product Name: | BBS 4 | | Synonyms: | BBS 4;2-PyrrolidinecarboxaMide, N-[2-(1,3-benzodioxol-5-yl)ethyl]-1-[2-(1H-iMidazol-1-yl)-6-Methyl-4-pyriMidinyl]-, (2R)- | | CAS: | 402934-09-2 | | MF: | C22H24N6O3 | | MW: | 420.46 | | EINECS: | | | Product Categories: | | | Mol File: | 402934-09-2.mol |  |
| | BBS 4 Chemical Properties |
| density | 1.43±0.1 g/cm3(Predicted) | | pka | 14.54±0.20(Predicted) |
| | BBS 4 Usage And Synthesis |
| Description | BBS4 is a potent, orally active and selective inducible nitric oxide synthase dimerization inhibitor. BBS4 inhibits the dimerization of iNOS monomers, thus preventing the formation of the dimeric, active form of the enzyme. BBS4 significantly ameliorated adjuvant-induced arthritis in a rat model. BBS4 blocks the formation of the protein-protein interaction present in the dimeric form of iNOS. BBS4 prevents systemic, cardiac, and pulmonary hemodynamic dysfunction in endotoxemic mice. |
| | BBS 4 Preparation Products And Raw materials |
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