| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:LPD-12
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| | AC-AO(C12)AEAAEKAAKYAAEAAEKAAKAO(C12)A-NH2 Basic information |
| Product Name: | AC-AO(C12)AEAAEKAAKYAAEAAEKAAKAO(C12)A-NH2 | | Synonyms: | AC-AO(C12)AEAAEKAAKYAAEAAEKAAKAO(C12)A-NH2;LIPOPEPTIDE DETERGENT-12;LPD-12;Ac-Ala-Orn(dodecanoyl)-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Tyr-Ala-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Ala-Orn(dodecanoyl)-Ala-NH trifluoroacetate salt | | CAS: | | | MF: | C131H224N32O37 | | MW: | 2839.37 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | AC-AO(C12)AEAAEKAAKYAAEAAEKAAKAO(C12)A-NH2 Chemical Properties |
| storage temp. | 2-8°C | | form | White lyophilized |
| | AC-AO(C12)AEAAEKAAKYAAEAAEKAAKAO(C12)A-NH2 Usage And Synthesis |
| General Description | A water soluble, amphiphilic α-helical, non-denaturing lipopeptide detergent (LPD) that forms small micelles (CMC <1 μM; micelle MW ~23,100; aggregation number ~8.1; partial specific volume ~0.77 cm3/g) and effectively mimics lipid bilayers. Shown to solubilize as well as stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~250 μM and [protein] ~22 μM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins. |
| | AC-AO(C12)AEAAEKAAKYAAEAAEKAAKAO(C12)A-NH2 Preparation Products And Raw materials |
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