Company Name: |
Shanghai Chaolan Chemical Technology Center
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Tel: |
QQ:65489617 15618227136 |
Email: |
info@SuperLan-chem.com |
Products Intro: |
Product Name:DEPTOR-IN-1 CAS:2615911-12-9 Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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Company Name: |
Absin Bioscience Inc.
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Tel: |
021-38015121 15000105423 |
Email: |
chenjw@absin.cn |
Products Intro: |
Product Name:DEPTOR-IN-1 CAS:2615911-12-9 Purity:98% Package:50mg
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| 4H,8H-Pyrano[2,3-f][1,3]benzoxazin-4-one, 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-9,10-dihydro-3-hydroxy- Basic information |
Product Name: | 4H,8H-Pyrano[2,3-f][1,3]benzoxazin-4-one, 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-9,10-dihydro-3-hydroxy- | Synonyms: | 4H,8H-Pyrano[2,3-f][1,3]benzoxazin-4-one, 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-9,10-dihydro-3-hydroxy-;DEPTOR-IN-1;DEPTORIN1,inhibit,DEPTOR IN 1,Inhibitor | CAS: | 2615911-12-9 | MF: | C24H16Cl2FNO4 | MW: | 472.29 | EINECS: | | Product Categories: | | Mol File: | 2615911-12-9.mol | |
| 4H,8H-Pyrano[2,3-f][1,3]benzoxazin-4-one, 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-9,10-dihydro-3-hydroxy- Chemical Properties |
Boiling point | 617.1±55.0 °C(Predicted) | density | 1.525±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | pka | 7.96±0.20(Predicted) |
| 4H,8H-Pyrano[2,3-f][1,3]benzoxazin-4-one, 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-9,10-dihydro-3-hydroxy- Usage And Synthesis |
Biological Activity | DEPTOR-IN-1 is a novel putative DEPTOR inhibitor with a Kd value of 9.3 μM. | References | [1]. Hou Y, et al. Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment. J Med Chem. 2021 Oct 28;64(20):14942-14954. |
| 4H,8H-Pyrano[2,3-f][1,3]benzoxazin-4-one, 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-9,10-dihydro-3-hydroxy- Preparation Products And Raw materials |
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