| Company Name: |
Qingdao Tenglong microwave technology co., LTD.
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0532-83818797 18561885118 |
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market@tlwb.com.cn |
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Product Name:L-ARGININE:HCL MICROBIOLOGICAL/PYROGEN TESTED (GUANIDO-15N2,98%+)
CAS:204633-92-1
Purity:98% Package:询问 Remarks:NLM-395-MPT-PK
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| Company Name: |
Reer Technology (Shanghai) Co., LTD
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| Tel: |
021-64400900 15800436310 |
| Email: |
bessey@reertech.com |
| Products Intro: |
Product Name:L-ARGININE:HCL MICROBIOLOGICAL/PYROGEN TESTED(GUANIDO-15N2,98%+)
CAS:204633-92-1
Purity:98% Package:G Remarks:NLM-395-MPT-PK
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| Company Name: |
Shanghai isotope chemical co.,ltd
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| Tel: |
021-021-51600108 13062666369 |
| Email: |
sales@chinaisotope.com |
| Products Intro: |
Product Name:L-ARGININE:HCL (GUANIDO-15N2, 98%+)
CAS:204633-92-1
Purity:98% Package:0.5 G Remarks:NLM-395-0.5
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| Company Name: |
Medical Isotopes
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1-(603) 635-1722 |
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stohler@medicalisotopes.com |
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| | L-Arginine-guanido-15N2HCl Basic information |
| | L-Arginine-guanido-15N2HCl Chemical Properties |
| storage temp. | Store at -20°C |
| | L-Arginine-guanido-15N2HCl Usage And Synthesis |
| Biological Activity | L-Arginine-15N2 ((S)-(+)-Arginine-15N2) hydrochloride is the 15N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. | | References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12.[3]. Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45.[4]. Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17. |
| | L-Arginine-guanido-15N2HCl Preparation Products And Raw materials |
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