Neothiobinupharidine

Neothiobinupharidine Basic information
Product Name:Neothiobinupharidine
Synonyms:Neothiobinupharidine;Dispiro[2H-quinolizine-3(4H),2'(3'H)-thiophene-4'(5'H),3''(4''H)-[2H]quinolizine], 6,6''-di-3-furanyldodecahydro-9,9''-dimethyl-, (2'R,3''R,6S,6''S,9R,9''R,9aS,9''aS)-
CAS:4850-09-3
MF:C30H42N2O2S
MW:494.73168
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Mol File:4850-09-3.mol
Neothiobinupharidine Structure
Neothiobinupharidine Chemical Properties
Melting point 159-160°C
Boiling point 601.1±55.0 °C(Predicted)
density 1.20±0.1 g/cm3(Predicted)
pka9.54±0.70(Predicted)
Safety Information
MSDS Information
Neothiobinupharidine Usage And Synthesis
DescriptionThis sulphur-containing alkaloid has been isolated from Nuphar luteurn and shown to have the above structure. It yields well-crystalline salts with mineral acids, e.g. the dihydrobromide which forms long prisms of the tetrahydrate from aqueous EtOH, m.p. l46-9°C; diperchlorate, m.p. 320°C (dec.) and the methiodide, m.p. 240-2°C.
ReferencesAchmatowicz, Wrobel., Tetrahedron Lett., 129 (1964)
Achmatowicz et ai., ibid, 927 (1964)
Crystal structure: Birnbaum., Tetrahedron Lett., 4149 (1965)
Neothiobinupharidine Preparation Products And Raw materials
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