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N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide

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N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:MRT67307
CAS:1190378-57-4
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Shandong chuangyingchemical Co., Ltd.
Tel: 18853181302
Email: sale@chuangyingchem.com
Products Intro: Product Name:MRT67307
CAS:1190378-57-4
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:MRT67307
CAS:1190378-57-4
Purity:98% Package:10mg Remarks:BOC Sciences also provides custom synthesis services for MRT67307.
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:n-(3-((5-cyclopropyl-2-((3-(4-morpholinylmethyl)phenyl)amino)-4-pyrimidinyl)amino)propyl)cyclobutanecarboxamide
CAS:1190378-57-4
Purity:0.99 Package:1kg
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:MRT67307；MRT67307 HCl
CAS:1190378-57-4
Purity:99.25% Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Basic information
Product Name:N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide
Synonyms:MRT67307;MRT67307 hydrochloride;N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxamide hydrochloride;MRT68921;N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide;MRT67307 (free base);IKKε/TBK1 Inhibitor II, MRT67307 - CAS 1190378-57-4 - Calbiochem;MRT67307 HCl
CAS:1190378-57-4
MF:C26H36N6O2
MW:464.6
EINECS:
Product Categories:NF-kB;API
Mol File:1190378-57-4.mol
N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Structure
N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Chemical Properties
density 1.270
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility H2O: soluble15mg/mL, clear
form powder
pka15.94±0.20(Predicted)
color white to light brown
InChIKeyUKBGBACORPRCGG-UHFFFAOYSA-N
Safety Information
WGK Germany 3
MSDS Information
N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Usage And Synthesis
UsesMRT67307 hydrochloride has been used to study its effect on LPS (lipopolysaccharide) -induced lysosome tubulation.
DefinitionChEBI: N-[3-[[5-cyclopropyl-2-[3-(4-morpholinylmethyl)anilino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide is an aromatic amine.
Biochem/physiol ActionsMRT67307 is an amino-pyrimidine derivative and has an IC50 value of 19. It is known to induce TLR (toll like receptor) mediated anti inflammatory cytokine generation. Also, MRT67307 prevents the secretion of cytokines associated with proinflammation.
targetIKKe
N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Preparation Products And Raw materials
Tag:N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide(1190378-57-4) Related Product Information