| Company Name: |
Hubei Jusheng Technology Co.,Ltd. |
| Tel: |
18871490254 |
| Email: |
linda@hubeijusheng.com |
| Products Intro: |
Product Name:Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-
CAS:960226-55-5
Purity:99% Package:5KG;1KG Remarks:C22H19N3O4
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| Company Name: |
BOC Sciences Gold
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| Tel: |
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| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Tadalafil-d3
CAS:960226-55-5
Purity:95% by HPLC; 95% atom D
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Tadalafil-d3
CAS:960226-55-5
Package:10Mg,1Mg
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- Tadalafil-D3
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- $282.00 / 10mg
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2023-05-27
- CAS:960226-55-5
- Min. Order: 10mg
- Purity: 96%
- Supply Ability: 100
- Tadalafil-D3
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- $0.00 / 5mg
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2023-05-27
- CAS:960226-55-5
- Min. Order: 1mg
- Purity: 96%
- Supply Ability: 50 mg
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| | Tadalafil-d3 Basic information |
| Product Name: | Tadalafil-d3 | | Synonyms: | Tadalafil-d3;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-;PubChem ID: 46782966;[2H3]-Tadalafil;Tadalafil D3Q: What is
Tadalafil D3 Q: What is the CAS Number of
Tadalafil D3 Q: What is the storage condition of
Tadalafil D3 Q: What are the applications of
Tadalafil D3 | | CAS: | 960226-55-5 | | MF: | C22H18N3O4 | | MW: | 388.39602 | | EINECS: | | | Product Categories: | Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Intermediates & Fine Chemicals,Chiral Reagents | | Mol File: | 960226-55-5.mol |  |
| | Tadalafil-d3 Chemical Properties |
| Melting point | 281-283°C | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), DMSO (Slightly) | | form | Solid | | color | White to Off-White | | Stability: | Unstable in Methanol | | InChI | InChI=1/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21+/s3 | | InChIKey | WOXKDUGGOYFFRN-PDIFIXMTNA-N | | SMILES | c12c3ccccc3nc1[C@H](c1cc3OCOc3cc1)N1C(=O)CN(C)C(=O)[C@H]1C2 |&1:9,27,r| |
| | Tadalafil-d3 Usage And Synthesis |
| Description | Tadalafil-d3 is intended for use as an internal standard for the quantification of tadalafil by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury. It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice. Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction. | | Chemical Properties | Tadalafil-d3 is White Solid | | Uses | Tadalafil-d3 is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Intended for use as an internal standard for the quantification of Tadalafil by GC- or LC-mass spectrometry. | | Uses | Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. |
| | Tadalafil-d3 Preparation Products And Raw materials |
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