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ChemPep, Inc.
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| Products Intro: |
Product Name:Z-NH-PEG5-CH2COOH
CAS:1449390-66-2
Purity:95% Package:1 g, 5 g Remarks:PEGylation Reagents
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| Company Name: |
T&W GROUP
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021-61551611 13296011611 |
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contact@trustwe.com |
| Products Intro: |
Product Name:CBZ-NH-PEG5-acetic acid
CAS:1449390-66-2
Purity:98% Package:按需包装
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| | Z-NH-5(ethylene glycol)-acetic acid Basic information |
| Product Name: | Z-NH-5(ethylene glycol)-acetic acid | | Synonyms: | Z-NH-5(ethylene glycol)-acetic acid;Z-NH-PEG5-CH2COOH;CBZ-NH-PEG5-acetic acid;CBZ-NH-PEG5-CH2COOH;5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;CbzNH-P5-CH2CO2H;inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH;CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester | | CAS: | 1449390-66-2 | | MF: | C20H31NO9 | | MW: | 429.46 | | EINECS: | | | Product Categories: | PEGylated Amino Acid | | Mol File: | 1449390-66-2.mol |  |
| | Z-NH-5(ethylene glycol)-acetic acid Chemical Properties |
| | Z-NH-5(ethylene glycol)-acetic acid Usage And Synthesis |
| Biological Activity | Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Z-NH-5(ethylene glycol)-acetic acid Preparation Products And Raw materials |
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