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Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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Product Name:Palmitoyl 3-carbacyclic Phosphatidic Acid
CAS:476310-22-2
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
MedBioPharmaceutical Technology Inc
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021-69568360 18916172912 |
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order@med-bio.cn |
| Products Intro: |
Product Name:Palmitoyl 3-carbacyclic Phosphatidic Acid
CAS:476310-22-2
Purity:98% Package:10mg; 500ug; 1mg; 5mg Remarks:Medbio
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
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Product Name:Palmitoyl 3-carbacyclic Phosphatidic Acid Exclusive
CAS:476310-22-2
Purity:95% Package:500μg;1mg;5mg
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| Company Name: |
Cayman Chemical Company
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(800) 364-9897 |
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cayman@caymanchem.com |
| Products Intro: |
Product Name:Palmitoyl 3-carbacyclic Phosphatidic Acid
CAS:476310-22-2
Package:>=95% Remarks:10010293
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| | Palmitoyl 3-carbacyclic Phosphatidic Acid Basic information |
| Product Name: | Palmitoyl 3-carbacyclic Phosphatidic Acid | | Synonyms: | Palmitoyl 3-carbacyclic Phosphatidic Acid;LJNWYINJKCNEPA-UHFFFAOYSA-N;Palmitoyl 3-carbacyclic Phosphatidic Acid Exclusive;Hexadecanoic acid, (2-hydroxy-2-oxido-1,2-oxaphospholan-5-yl)methyl ester | | CAS: | 476310-22-2 | | MF: | C20H39O5P | | MW: | 390.49 | | EINECS: | | | Product Categories: | | | Mol File: | 476310-22-2.mol |  |
| | Palmitoyl 3-carbacyclic Phosphatidic Acid Chemical Properties |
| solubility | PBS (pH 7.2): 0.5 mg/ml | | form | A crystalline solid |
| | Palmitoyl 3-carbacyclic Phosphatidic Acid Usage And Synthesis |
| Description | Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn-2 hydroxy group forms a 5-membered ring with the sn-3 phosphate. Carba-derivatives of cPA (ccPA) are modified at the sn-2 (2-ccPA) or sn-3 (3-ccPA) linkage, preventing the opening of cPA to produce LPA. Palmitoyl 3-ccPA is a cyclic LPA analog that contains the 16:0 fatty acid, palmitate, at the sn-1 position of the glycerol backbone. At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (81.9%) or LPA (98.9%) without affecting proliferation. 3-ccPA 16:0, at 0.1-25 μM, significantly inhibits autotaxin, an enzyme that is important in cancer cell survival, growth, migration, invasion and metastasis. |
| | Palmitoyl 3-carbacyclic Phosphatidic Acid Preparation Products And Raw materials |
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