| Company Name: |
Thermo Fisher Scientific
|
| Tel: |
021-61621892 400-650-5118 |
| Email: |
sales.china@thermofisher.com |
| Products Intro: |
Product Name:Ubiquitin Polyclonal Antibody
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| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:Ubiquitin Polyclonal Antibody
Remarks:13724
|
|
| | Ubiquitin Polyclonal Antibody Basic information |
| | Ubiquitin Polyclonal Antibody Chemical Properties |
| | Ubiquitin Polyclonal Antibody Usage And Synthesis |
| Description | Ubiquitin is a regulatory protein encoded by three gene classes in humans, which code for fusion proteins between ubiquitin and zinc-finger proteins, ribosomal proteins, or ubiquitin repeats that are cleaved by esterases to release monomeric ubiquitin. It is ubiquitously expressed and highly conserved among eukaryotic species. Ubiquitin is conjugated to misfolded, abnormal, short-lived, or foreign proteins by ubiquitin-conjugating enzymes (E2) and substrate-specific ubiquitin ligases (E3) to target them for degradation by the 26S proteasome or lysosome. It is also conjugated to proteins to modify cell signaling through regulation of protein-protein interactions, activity, or subcellular localization. Dysregulation of ubiquitination has been implicated in the pathogenesis of neurodegenerative diseases, including Parkinson’s and Alzheimer’s diseases. Cayman’s Ubiquitin Polyclonal Antibody can be used for immunocytochemistry (ICC), immunofluorescence (IF), immunohistochemistry (IHC), immunoprecipitation (IP), and Western blot (WB) applications. The antibody recognizes ubiquitin at ~10 kDa from human samples. |
| | Ubiquitin Polyclonal Antibody Preparation Products And Raw materials |
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