- Boc-Val-Cit-PAB-PNP
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- $0.00 / 1g
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2024-03-29
- CAS:870487-10-8
- Min. Order: 1g
- Purity: >99.00%
- Supply Ability: 1g
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| | Boc-Val-Cit-PAB-PNP Basic information |
| Product Name: | Boc-Val-Cit-PAB-PNP | | Synonyms: | Boc-Val-Cit-PAB-PNP;BOC-Val-cit-pab;tert-butyl ((5)-3-methyl-1-(((5)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate;Boc-Val-Cit-PABC-PNP;Boc-Val-Cit-PAB-PNB;L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-;t-Butyloxycarbonyl-valyl-citrullyl-(4-aminobenzyl)-(4-nitrophenyl)carbonate;Benzeneethanol,6-iodo- | | CAS: | 870487-10-8 | | MF: | C30H40N6O10 | | MW: | 644.67 | | EINECS: | | | Product Categories: | Linker;ADC LINKER;ADCs | | Mol File: | 870487-10-8.mol |  |
| | Boc-Val-Cit-PAB-PNP Chemical Properties |
| Boiling point | 896.0±65.0 °C(Predicted) | | density | 1.291±0.06 g/cm3(Predicted) | | solubility | DMSO : 250 mg/mL (387.80 mM; Need ultrasonic) | | pka | 11.25±0.46(Predicted) |
| | Boc-Val-Cit-PAB-PNP Usage And Synthesis |
| Description | Boc-Val-Cit-PAB-PNB is a cleavable peptide ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell.PNP can be substituted by amine bearing molecules. |
| | Boc-Val-Cit-PAB-PNP Preparation Products And Raw materials |
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