URSODEOXYCHOLIC-2,2,4,4-D4 ACID

URSODEOXYCHOLIC-2,2,4,4-D4 ACID Suppliers list
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:(4R)-4-[(3R,5R,7S,8R,9S,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
CAS:347841-46-7
Purity:0.99 Package:5KG;1KG
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:(4R)-4-[(3R,5S,7S,8R,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
CAS:347841-46-7
Purity:95% Remarks:MC741778
Company Name: S.Z. PhyStandard Bio-Tech. Co., Ltd.  
Tel: 0755-4000505016 13380397412
Email: 3001272453@qq.com
Products Intro: Product Name:Ursodiol-d4 (Ursodeoxycholic Acid-d4)
CAS:347841-46-7
Purity:99% HPLC Package:10mg;25mg;50mg;100mg
Company Name: Clearsynth Labs Limited  
Tel: +91-22-26355700
Email: info@clearsynth.com
Products Intro: Product Name:Ursodeoxycholic-d4 Acid
CAS:347841-46-7
Remarks:CS-C-01526
Company Name: ChemStrong Scientific Co.,Ltd  
Tel: 0755-0755-66853366 13670046396
Email: sales@chem-strong.com
Products Intro: Product Name:Ursodeoxycholic Acid-d4
CAS:347841-46-7
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
URSODEOXYCHOLIC-2,2,4,4-D4 ACID Basic information
Product Name:URSODEOXYCHOLIC-2,2,4,4-D4 ACID
Synonyms:URSODEOXYCHOLIC-2,2,4,4-D4 ACID;Ursodeoxycholic-d4 Acid;(4R)-4-[(3R,5R,7S,8R,9S,10S,13R,14S,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;(4R)-4-[(3R,5R,7S,8R,9S,10S,13R,17R)-2,2,4,4-tetradeuterio-3,7-dihydroxy-10,13-dimethyl-3,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;Ursodiol-d4 (Ursodeoxycholic Acid-d4);Ursodeoxycholic acid-[d4] (Solution);URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 95% CHEMICAL PURITY;URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
CAS:347841-46-7
MF:C24H40O4
MW:392.58
EINECS:
Product Categories:Bile Acids - 13C & 2H
Mol File:347841-46-7.mol
URSODEOXYCHOLIC-2,2,4,4-D4 ACID Structure
URSODEOXYCHOLIC-2,2,4,4-D4 ACID Chemical Properties
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly),
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
URSODEOXYCHOLIC-2,2,4,4-D4 ACID Usage And Synthesis
DescriptionUrsodeoxycholic acid-d4 (UDCA-d4) is intended for use as an internal standard for the quantification of UDCA (Item No. 15121) by GC- or LC-MS. UDCA is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.
UsesUrsodeoxycholic Acid-d4 is a deuterated form of Ursodeoxcholic Acid (U850000), which is used as an anticholelithogenic. Ursodeoxcholic Acid is an epimer with Chenodiol with respect to the hydroxyl group at C7. Ursodeoxycholic Acid-d4 was used as an internal standard for rapid quantification of bile acids by liquid chromatography-tandem mass spectrometry.
URSODEOXYCHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials
Tag:URSODEOXYCHOLIC-2,2,4,4-D4 ACID(347841-46-7) Related Product Information
URSODEOXYCHOLIC ACID ACYL-B-D-GLUCURONIDE Glycoursodeoxycholic Acid URSODEOXYCHOLIC ACID-24-13C Ursodeoxycholic acid Ursodeoxycholic Acid-d5 Ursodeoxycholic Acid Methyl Ester-d5 Taurolithocholic-d4 Acid (3α,5β,7β)- 3,7,22-Trihydroxycholan-24-oic Acid α-Muricholic Acid (3b,5b,7a,12a)-3,7,12-trihydroxy-Cholan-24-oic acid (4R)-4-[(3S,5S,7S,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(3S,5R,8S,9S,10S,12S,13R,14S)-1,3,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid Ursodeocycholic Acid-[d4]-3-Sulfate Sodium Salt Ursodeocycholic Acid-3-Sulfate Sodium Salt (3a,5b,7a,12b)-3,7,12-trihydroxy-Cholan-24-oic acid 3,7-DIKETO-5BETA-CHOLAN-24-OIC ACID LITHOCHOLIC ACID 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid