Company Name: |
Changzhou Hopschain Chemical Co.,Ltd.
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Tel: |
0519-85528066 13775048983 |
Email: |
sales@hopschem.com |
Products Intro: |
Product Name:tert-butyl N-(2-bromo-6-fluorophenyl)carbamate CAS:1057720-25-8 Purity:95+% Package:100mg;250mg;500mg;1g;2.5g;5g;10g
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Company Name: |
Xi'an Zhenghao Biotechnology Co., Ltd
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Tel: |
19829389091 |
Email: |
399787610@qq.com |
Products Intro: |
Product Name:tert-butyl (2-bromo-6-fluorophenyl)carbamate CAS:1057720-25-8 Purity:95% Package:1G;5G;10G~500G;1KG;10KG;
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Company Name: |
Shanghai Haohong Pharmaceutical Co., Ltd.
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Tel: |
400-8210725 4008210725 |
Email: |
malulu@leyan.com |
Products Intro: |
Product Name:tert-Butyl (2-bromo-6-fluorophenyl)carbamate CAS:1057720-25-8 Purity:95%
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| tert-butyl (2-bromo-6-fluorophenyl)carbamate Basic information |
| tert-butyl (2-bromo-6-fluorophenyl)carbamate Chemical Properties |
Melting point | 93-94 °C(Solv: ligroine (8032-32-4)) | Boiling point | 270.4±30.0 °C(Predicted) | density | 1.459±0.06 g/cm3(Predicted) | pka | 11.85±0.70(Predicted) |
| tert-butyl (2-bromo-6-fluorophenyl)carbamate Usage And Synthesis |
Uses | tert-Butyl N-(2-Bromo-6-fluorophenyl)carbamate can be used in the preparation of indolines, isoquinolinones, and indoles by palladium-catalyzed annulation of substituted haloanilines or substituted halobenzamides with norbornadiene as an acetylene synthon. It can be useful in the preparation of ring-fluorinated N-Boc methyleneindolines via ortho lithiation and bromination of fluorinated anilines followed by nucleophilic addition of propargyl bromide and radical-induced ring closure. It can be useful in the synthesis of indoles via intramolecular 5-endo-dig carbocupration from N-aryl-ynamides. |
| tert-butyl (2-bromo-6-fluorophenyl)carbamate Preparation Products And Raw materials |
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