| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
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| Products Intro: |
CAS:4599-60-4
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | PENIMEPICYCLINE Basic information |
| Product Name: | PENIMEPICYCLINE | | Synonyms: | PENIMEPICYCLINE;-3,6,10,12,12a-pentahydroxy-n-((4-(2-hydroxyethyl)-1-piperazinyl)methyl)-6-me;duamine;henoxyacetamido)-,compd.with4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro;hydrocycline;mepicyclinepenicillinate;penetracyne;thyl-1,11-dioxo-2-naphthacenecarboxamide(1:1) | | CAS: | 4599-60-4 | | MF: | C45H56N6O14S | | MW: | 937.03 | | EINECS: | 225-002-0 | | Product Categories: | | | Mol File: | 4599-60-4.mol |  |
| | PENIMEPICYCLINE Chemical Properties |
| alpha | D20 -50.5° (c = 2 in methanol) | | storage temp. | 2-8°C |
| | PENIMEPICYCLINE Usage And Synthesis |
| Originator | Penimepicyclina ,Elenco Farmaci | | Definition | ChEBI: A penicillinate salt obtained by combining equimolar amounts of phenoxymethylpenicillin and pipacycline. | | Manufacturing Process | N-(41-β-hydroxyethyl-11-piperazinylmethyl)tetracycline was obtained by reaction of tetracycline with 1-(2-hydroxyethyl)piperazine in the presence of formaldehyde.
8.6 g of N-(41-β-hydroxyethyl-11-piperazinylmethyl)tetracycline and 35.0 gphenoxymethyl-penicilline, were dissolved in 300 ml methanol, with agitation. The solution was filtered on a Buchner filter, and the filtrate was taken up with 900 ml anhydrous ether with strong agitation, again filtered under pressure, and the filter cake was washed twice with 50 ml anhydrous ether. The product was; dried in vacuum. 84.0 g were obtained of a penimepicycline as yellowish white powder. | | Therapeutic Function | Antibiotic |
| | PENIMEPICYCLINE Preparation Products And Raw materials |
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