Macromerine

Macromerine Basic information
Product Name:Macromerine
Synonyms:Macromerine;[R,(-)]-α-[(Dimethylamino)methyl]-3,4-dimethoxybenzenemethanol;Benzenemethanol, α-[(dimethylamino)methyl]-3,4-dimethoxy-, (αR)-
CAS:19751-75-8
MF:C12H19NO3
MW:225.28
EINECS:
Product Categories:Benzene series
Mol File:19751-75-8.mol
Macromerine Structure
Macromerine Chemical Properties
Melting point 66-67.SoC
Safety Information
MSDS Information
Macromerine Usage And Synthesis
DescriptionHodgkins and his co-workers have isolated this alkaloid from Coryphantha macromeris (Engelm.) Lem. Britton and Rose (Syn. Thelocactus macromeris (Engelm.) L. Benson and it has subsequently been discovered in C. runyonii. It is a laevorotatory base with [α]25D - 42.61° (c 2.0, EtOH) or - 147.01° (c 3.9, CHC13). The synthetic (±)-form has a higher m.p. l46-7°C and yields a crystalline picrate, m.p. 147°C. Spectroscopic and chemical data are in accord with the structure (-)- -(3 :4-dimethoxyphenyl)- -(dimethylamino)ethanol.
ReferencesHodgkins, Brown, Massingill., Tetrahedron Lett., 1321 (1967) Below et al., J. Pharm. Sci., 57,515 (1968)
Macromerine Preparation Products And Raw materials
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