BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Suppliers list
Company Name: Career Henan Chemica Co
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Products Intro: Product Name:3,5-dichloro-N-((1-((2,2-dimethyltetrahydro- 2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide
CAS:918430-49-6
Purity:98% Package:1g;1USD
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Products Intro: CAS:918430-49-6
Purity:0.99 Package:1000KG;100KG;5KG;1KG
Company Name: Amadis Chemical Company Limited
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Products Intro: Product Name:3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide
CAS:918430-49-6
Purity:0.97 Package:mgs,gs,kgs Remarks:A917029
Company Name: Acesys Pharmatech  
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Products Intro: Product Name:3,5-dichloro-N-((1-((2,2-dimethyltetrahydro- 2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide
CAS:918430-49-6
Purity:97% Package:5g;100g;1Kg
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Products Intro: Product Name:3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide
CAS:918430-49-6
Purity:98%+ Package:5g;25g;100g;500g;1kg;5kg;25kg;100kg Remarks:BX30628
BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Basic information
Product Name:BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-
Synonyms:BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-;BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-;3,5-Dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-dimethyl-2H-pyran-4-yl)methyl]-4-piperidinyl]methyl]Benzamide;3,5-dichloro-N-((1-((2,2-diMethyltetrahydro-2H-pyran-4-yl)Methyl)-4-fluoropiperidin-4-yl)Methyl)benzaMide;3,5-Dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-dimethyl-2H-pyran-4-yl)methyl]-4-piperidinyl]methyl]ben;(Rac)-TTA-P2
CAS:918430-49-6
MF:C21H29Cl2FN2O2
MW:431.37
EINECS:
Product Categories:
Mol File:918430-49-6.mol
BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Structure
BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Chemical Properties
Boiling point 510.1±50.0 °C(Predicted)
density 1.25±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in DMSO (10 mg/ml)
form solid
pka13.65±0.46(Predicted)
color Tan
Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
MSDS Information
BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Usage And Synthesis
DescriptionTTA-P2 (918430-49-6) is a potent (IC50 = 100 nM), specific, and reversible antagonist of T-type calcium channels with no activity at high voltage calcium channels.1,2 Highly potent in two animal models of pain in vivo.3
ReferencesShipe et al. (2008), Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist; J. Med. Chem., 51 3692 Dreyfus et al. (2010), Selective T-type calcium channel block in thalamic neurons reveals channel redundancy and physiological impact of I(T)window; J. Neurosci., 30 99 Choe et al. (2011), TTA-P2 is a potent and selective blocker of T-type calcium channels in rat sensory neurons and a novel antinociceptive agent; Mol. Pharmacol., 80 900
BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Preparation Products And Raw materials
Tag:BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-(918430-49-6) Related Product Information
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