| Company Name: |
NCE Biomedical Co.,Ltd.
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| Tel: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
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| Products Intro: |
Product Name:PF-4942847
CAS:1046859-34-0
Purity:99% HPLC Package:50Mg,100Mg,500Mg,1g,5g,10g,50g,100g,500g,1kg Remarks:XYA0072
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| Company Name: |
LETOPHARM LIMITED
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| Tel: |
+86-21-5821 5861 |
| Email: |
sales@letopharm.com |
| Products Intro: |
Product Name:PF-4942847
CAS:1046859-34-0
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| Company Name: |
SPIRO PHARMA
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| Tel: |
|
| Email: |
eric_feng1954@126.com |
| Products Intro: |
Product Name:PF-4942847
CAS:1046859-34-0
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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| | PF-4942847 Basic information |
| Product Name: | PF-4942847 | | Synonyms: | PF-4942847;2-aMino-4-(2,4-dichloro-6-(2-(4-fluoro-4,5-dihydropyrazol-1-yl)ethoxy)phenyl)-N-(2,2,2-trifluoroethyl)-5H-pyrrolo[3,4-d]pyriMidine-6(7H)-carboxaMide;2-Amino-4-[2,4-dichloro-6-[2-(1H-pyrazol-1-yl)ethoxy]phenyl]-5,7-dihydro-N-(2,2,2-trifluoroethyl)-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide;PF-04942487;6H-Pyrrolo[3,4-d]pyrimidine-6-carboxamide, 2-amino-4-[2,4-dichloro-6-[2-(1H-pyrazol-1-yl)ethoxy]phenyl]-5,7-dihydro-N-(2,2,2-trifluoroethyl)- | | CAS: | 1046859-34-0 | | MF: | C20H18Cl2F3N7O2 | | MW: | 516.3 | | EINECS: | | | Product Categories: | | | Mol File: | 1046859-34-0.mol |  |
| | PF-4942847 Chemical Properties |
| | PF-4942847 Usage And Synthesis |
| Uses | A novel potent, selective, and orally bioavailable pyrrolodinopyrimidine-containing inhibitor of heat shock protein 90 (Hsp90). It has been shown to induce degradation of multiple client proteins, cell-cycle block, apoptosis, and inhibits cell proliferation in triple-negative breast cancer (TNBC) lines, subsequently leading to tumor growth inhibition in mouse xenograft models. |
| | PF-4942847 Preparation Products And Raw materials |
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