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batroxostatin

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batroxostatin Basic information
Product Name:batroxostatin
Synonyms:batroxostatin
CAS:130357-67-4
MF:
MW:0
EINECS:
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Mol File:Mol File
batroxostatin Structure
batroxostatin Chemical Properties
Safety Information
MSDS Information
batroxostatin Usage And Synthesis
Enzyme inhibitorThis cysteine-rich, 71-residue disintegrin (MW = 7602.46 g/mol; CAS 130357-67-4), from the snake Bothrops atrox (Barba amarilla) contains an RGD loop that facilitates high-affinity binding to integrins in a manner that inhibits ADP-induced platelet aggregation (IC50 = 133 nM), about 1000- times higher than that of Arg-Gly-Asp-Ser tetrapeptide. In addition, batroxostatin was about 400-times more potent than Arg-Gly-Asp-Ser at inhibiting melanoma cell adhesion to fibronectin. When covalently attached to plastic culture dishes, batroxostatin promoted adhesion of melanoma cells.
batroxostatin Preparation Products And Raw materials
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