HELIOTRINE

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Products Intro: Product Name:7R-Heliotrine
CAS:59532-50-2
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Products Intro: Product Name:Heliotrine
CAS:59532-50-2
HELIOTRINE Basic information
Product Name:HELIOTRINE
Synonyms:HELIOTRINE;Nsc30620;Sincamidine;Epiheliotrine;7R-Heliotrine;Butanoic acid, 2-hydroxy-2-[(1R)-1-methoxyethyl]-3-methyl-, [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S)-
CAS:59532-50-2
MF:C16H27NO5
MW:313.39
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Mol File:Mol File
HELIOTRINE Structure
HELIOTRINE Chemical Properties
Boiling point 450.7±45.0 °C(Predicted)
density 1.19±0.1 g/cm3(Predicted)
pka12.12±0.29(Predicted)
Safety Information
MSDS Information
HELIOTRINE Usage And Synthesis
DescriptionThis amorphous hepatotoxic alkaloid is present in Amsinckia intermedia Fisch & Mey. Alkaline hydrolysis gives retronecine and an acid, C8H16/sub>04 , forming colourless needles when crystallized from C6H6/sub> , m.p. 138-9°C; [α]20D + 5.8° (c 0.52, EtOH). Two hydroxyl groups are present in the alkaloid, one in the side chain and the other in the pyrrolizidine ring.
UsesHeliotrine is a monoester pyrrolizidine alkaloid that can be found in the seeds of Heliotropium indicum, one of the most widely used herbs in India. Heliotrine exhibits mutagenic activity and ganglion blocking activity.
ReferencesCulvenor, Smith., Austral. J. Chem., 19,1955 (1966)
HELIOTRINE Preparation Products And Raw materials
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