- Bardoxolone
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- $100.00 / 25KG
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2023-01-31
- CAS:890707-28-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5000kg/week
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| | Bardoxolone Basic information |
| Product Name: | Bardoxolone | | Synonyms: | 2-Amino-5-chloro-N,3-dimethylbenzamide 98%;Benzamide, 2-amino-5-chloro-N,3-dimethyl-;Bardoxolone Powder C9h11cln2o;cas 890707-28-5 98%;cas 890707-28-5 Coragen intermediate;cas 890707-28-5 98% Coragen intermediate;2-Amino-5-chloro-N,3-dimethylbenzamide;2-Amino-5-chloro-N,3-dimethylbenzamide, 95+% | | CAS: | 890707-28-5 | | MF: | C9H11ClN2O | | MW: | 198.65 | | EINECS: | 618-233-7 | | Product Categories: | | | Mol File: | 890707-28-5.mol |  |
| | Bardoxolone Chemical Properties |
| Melting point | 130-132 °C | | Boiling point | 308.8±42.0 °C(Predicted) | | density | 1.239 | | vapor pressure | 0-0Pa at 20-25℃ | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | pka | 14.24±0.46(Predicted) | | form | Solid | | color | Off-White to Light Brown | | InChI | InChI=1S/C9H11ClN2O/c1-5-3-6(10)4-7(8(5)11)9(13)12-2/h3-4H,11H2,1-2H3,(H,12,13) | | InChIKey | WOBVZGBINMTNKL-UHFFFAOYSA-N | | SMILES | C(NC)(=O)C1=CC(Cl)=CC(C)=C1N | | LogP | 1.7 at 25℃ | | Surface tension | 67.8mN/m at 249.3mg/L and 20.4℃ |
| | Bardoxolone Usage And Synthesis |
| Chemical Properties | Off-white powder | | Uses | Bardoxolone is a synthetic oleanane triterpenoid that exerts multifunctional activities in the control of cellular growth and differentiation. Bardoxolone is capable of activating the transcription factor peroxisome proliferator activator receptor-γ (PPARγ), its apoptotic effects in malignant cells have been shown to occur independently of PPARγ. Bardoxolone was developed as an potential drug for the improvement of hyperglycemia, proteinuria, glomerulus structure, serum creatine, which may in turn be beneficial to treat diabetic kidney diseases, cancer and thromboembolic events. |
| | Bardoxolone Preparation Products And Raw materials |
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