Begacestat

Begacestat Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Begacestat;GSI-953
CAS:769169-27-9
Purity:98.00% Package:1 mg;10 mg;5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:Begacestat
CAS:769169-27-9
Purity:NLT 98% Remarks:MC571082
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:GSI-953
CAS:769169-27-9
Package:100Mg,10Mg
Company Name: Chemsky (shanghai) International Co.,Ltd  
Tel: 021-50135380
Email: shchemsky@sina.com
Products Intro: Product Name:GSI-953;5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxyMethyl)-2-(trifluoroMethyl)propyl]-2-thiophenesulfonaMide; Begacestat; GSI 953;
CAS:769169-27-9
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
Company Name: shanghai cooperpharm co.,LTD .  
Tel: +86-021-58975553
Email: sales@cooperpharm.com
Products Intro: Product Name:(S)-5-chloro-N-(4,4,4-trifluoro-1-hydroxy-3-(trifluoroMethyl)butan-2-yl)thiophene-2-sulfonaMide
CAS:769169-27-9
Purity:99%HPLC Package:5OMg,,250Mg,1g,10g,250g,1kg,5kg
Begacestat Basic information
Product Name:Begacestat
Synonyms:Begacestat;Begacestat(GSI-953);GSI-953;5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxyMethyl)-2-(trifluoroMethyl)propyl]-2-thiophenesulfonaMide;(2S)-S-(5-chlorothiophen-2-yl)-4,4,4-trifluoro-1-hydroxy-N-Methyl-3-(trifluoroMethyl)butane-2-sulfonaMido;5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2- (trifluoromethyl)propyl] thiophene-2-sulfonamide;2-Thiophenesulfonamide, 5-chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]-;Begacestat (Synonyms: GSI-953)
CAS:769169-27-9
MF:C9H8ClF6NO3S2
MW:391.74
EINECS:
Product Categories:Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pfizer Compounds;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:769169-27-9.mol
Begacestat Structure
Begacestat Chemical Properties
Melting point 153-155°C
Boiling point 355℃
density 1.642
Fp 169℃
storage temp. 2-8°C
solubility DMSO: ≥15mg/mL
form powder
pka8.16±0.50(Predicted)
color white to tan
Safety Information
WGK Germany 3
MSDS Information
Begacestat Usage And Synthesis
UsesBegacestat (GSI-953) is a selective β-secretase inhibitor that selectively inhibits cleavage of APP over Notch. GSI-953 is used for treating diseases such as cancer in relation to prevention of intestinal secretory metaplasia.
Begacestat Preparation Products And Raw materials
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