| Company Name: |
ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396 |
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sales@chem-strong.com |
| Products Intro: |
Product Name:Milbemycin A3 Oxime; Milbemite Impurity 2
CAS:114177-14-9
Purity:95% HPLC Package:10mg;25mg;50mg
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| | MilbeMycin A3 OxiMe Basic information |
| Product Name: | MilbeMycin A3 OxiMe | | Synonyms: | MilbeMycin A3 OxiMe;5-OxoMilbeMycin A3 oxiMe;Milbemycin Impurity 10(Milbemycin A3 Oxime);5-ketomilbemycin A3 5-oxime;Milbemycin B, 5-demethoxy-28-deoxy-6,28-epoxy-5-(hydroxyimino)-25-methyl-, (6R,25R)-;Milbemite Impurity 2 | | CAS: | 114177-14-9 | | MF: | C31H43NO7 | | MW: | 541.68 | | EINECS: | | | Product Categories: | | | Mol File: | 114177-14-9.mol |  |
| | MilbeMycin A3 OxiMe Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml | | form | A crystalline solid |
| | MilbeMycin A3 OxiMe Usage And Synthesis |
| Description | Milbemycin A3 oxime is an anthelmintic, a derivative of milbemycin A3 , and a component of milbemycin oxide . It reduces the number of microfilariae of the heartworm D. immitis in the blood of naturally infested dogs by 85.2% when administered at a dose of 0.05 mg/kg. Formulations containing milbemycin A3 oxime, in combination with milbemycin A4 oxime, have been used in the treatment of parasitic infections in dogs. | | Uses | Milbemycin A3 oxime is the minor component of the anti-parasitic product milbemycin oxime. | | Uses | Milbemycin A3 oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of milbemycin A3. Milbemycin A3 oxime is the minor component (~30%) in the commercial product milbemycin oxime, marketed for endo- and exo-parasite infections. Like the other milbemycin/avermectins, milbemycin A3 oxime acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking. |
| | MilbeMycin A3 OxiMe Preparation Products And Raw materials |
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