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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid

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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Suppliers list
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Email: sales@alchempharmtech.com
Products Intro: Product Name:2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)acetic acid
CAS:378247-75-7
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-09068
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 15093356674;
Email: laboratory@coreychem.com
Products Intro: Product Name:2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)acetic acid
CAS:378247-75-7
Purity:95.0% Package:1g;1USD
Company Name: GL Biochem (Shanghai) Ltd.
Tel: +86-021-61263370 +86-18901917034
Email:
Products Intro: Product Name:Fmoc-7-aminocoumarin-4-acetic acid
CAS:378247-75-7
Purity:NLT 98% Package:25g, 100g, 500g, 1kg, 5kg, 25kg Remarks:Brand: GL Biochem
Company Name: Nextpeptide Inc
Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Products Intro: Product Name:Fmoc-ACA-OH
CAS:378247-75-7
Purity:98% Min. Package:5KG;1KG
Company Name: Shanghai Acmec Biochemical Technology Co., Ltd.
Tel: +undefined18621343501
Email: product@acmec-e.com
Products Intro: Product Name:2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)acetic acid
CAS:378247-75-7
Purity:95% Package:100mg, 1g, 250mg
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Basic information
Product Name:[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
Synonyms:[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid;2-(7-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-oxo-2H-chroMen-4-yl)acetic acid;7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-2H-1-benzopyran-4-acetic acid;7-N-Fmoc-aminocoumarin-4-acetic acid;2-[7-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-2-oxo-1-benzopyran-4-yl]acetic acid;2H-1-Benzopyran-4-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-;N-Fmoc-Aminocoumarin-4-acetic acid;Fmoc-7-aminocoumarin-4-acetic acid
CAS:378247-75-7
MF:C26H19NO6
MW:441.43
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Mol File:378247-75-7.mol
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Structure
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Chemical Properties
Melting point 273-276 °C
Boiling point 660.5±55.0 °C(Predicted)
density 1.418±0.06 g/cm3(Predicted)
storage temp. Store at +2°C to +8°C.
pka4.23±0.10(Predicted)
Safety Information
MSDS Information
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Usage And Synthesis
General DescriptionFmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates. Fmoc-ACA-OH [1] must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled withy HATU/collidine [2]. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases [3]. Treatment of the ACC peptide obtained after TFA cleavage with aqueous base causes facile decarboxylation and formation of the AMC peptide.
[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Preparation Products And Raw materials
Raw materialsETHYL (3-HYDROXYPHENYL)CARBAMATE-->7-Amino-4-carboxymethylcoumarin-->3-Aminophenol-->9-Fluorenylmethyl chloroformate
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