| Company Name: |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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| Tel: |
17702719238 17702719238 |
| Email: |
sales@sun-shinechem.com |
| Products Intro: |
Product Name:L-778123
CAS:183499-57-2
Purity:98% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g
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| | L-778123 Basic information |
| Product Name: | L-778123 | | Synonyms: | 4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]Benzonitrile;Benzonitrile, 4-[[5-[[4-(3-chlorophenyl)-3-oxo-1-piperazinyl]methyl]-1H-imidazol-1-yl]methyl]-;4-[5-[4-(3-Chlorophenyl)-3-oxopiperazin-1-ylmethyl]imidazol-1-ylmethyl]benzonitrile;4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile;123;L 778;L-778;L-778123 free base | | CAS: | 183499-57-2 | | MF: | C22H20ClN5O | | MW: | 405.88 | | EINECS: | | | Product Categories: | | | Mol File: | 183499-57-2.mol |  |
| | L-778123 Chemical Properties |
| Boiling point | 698.9±55.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml,Ethanol: 10 mg/ml | | form | A crystalline solid | | pka | 7.07±0.20(Predicted) |
| | L-778123 Usage And Synthesis |
| Definition | ChEBI: L-778,123 (free base) is a member of the class of imidazoles that is 1H-imidazole substituted by (4-cyanophenyl)methyl and [4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl groups at positions 1 and 5, respectively. It is a dual inhibitor of FPTase and GGPTase-I. It has a role as an EC 2.5.1.58 (protein farnesyltransferase) inhibitor, an EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor and an antineoplastic agent. It is a member of monochlorobenzenes, a piperazinone, a member of imidazoles, a tertiary amino compound and a nitrile. |
| | L-778123 Preparation Products And Raw materials |
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