MPEG16-NH2 manufacturers
- m-PEG16-amine
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- $0.00 / 500mg
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2024-03-29
- CAS:907577-50-8
- Min. Order: 500mg
- Purity: >95.00%
- Supply Ability: 500mg
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| | MPEG16-NH2 Basic information |
| Product Name: | MPEG16-NH2 | | Synonyms: | MPEG16-NH2;mPEG16-NH2;mPEG??-NH?;MeO-16eg-NH2;mPEG16-NH2/3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-Hexadecaoxanonatetracontan-1-amine;3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-Hexadecaoxanonatetracontan-1-amine | | CAS: | 907577-50-8 | | MF: | C33H69NO16 | | MW: | 735.9 | | EINECS: | | | Product Categories: | | | Mol File: | 907577-50-8.mol |  |
| | MPEG16-NH2 Chemical Properties |
| Boiling point | 699.1±50.0 °C(Predicted) | | density | 1.084±0.06 g/cm3(Predicted) | | pka | 8.74±0.10(Predicted) |
| | MPEG16-NH2 Usage And Synthesis |
| Biological Activity | m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | MPEG16-NH2 Preparation Products And Raw materials |
| Raw materials | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Hexadecaoxanonatetracontan-49-ol |
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