| Company Name: |
Artis Biotech Co. Ltd.
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| Tel: |
19138486554 18582380095 |
| Email: |
sales@artisbio.com |
| Products Intro: |
Product Name:Lopinavir-d8
CAS:1322625-54-6
Purity:98% HPLC Package:5mg 20mg 50mg 100mg 200mg 1g
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| Company Name: |
Nanjing Haolv Biotechnology Co.,Ltd
|
| Tel: |
025-84622273 02584622273; |
| Email: |
kexin.zhou@haolvbiotech.com |
| Products Intro: |
Product Name:Lopinavir-d8
CAS:1322625-54-6
Purity:98%D Package:5g;10g;25g
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Lopinavir-d8
CAS:1322625-54-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
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| | Lopinavir-d8 Basic information |
| Product Name: | Lopinavir-d8 | | Synonyms: | LOPINAVIR-D8;2,3,4,4,4-pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide | | CAS: | 1322625-54-6 | | MF: | C37H40D8N4O5 | | MW: | 636.850114224 | | EINECS: | | | Product Categories: | | | Mol File: | 1322625-54-6.mol |  |
| | Lopinavir-d8 Chemical Properties |
| Melting point | >96°C (dec.) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | Off-White to Pale Beige | | Stability: | Hygroscopic |
| | Lopinavir-d8 Usage And Synthesis |
| Description | Lopinavir-d8 is intended for use as an internal standard for the quantification of lopinavir by GC- or LC-MS. Lopinavir is a potent HIV-1 protease inhibitor (Ki = 1.3 pM for wild-type enzyme). It inhibits the replication of clinical isolates of HIV-1 (EC50s = 5-52 nM). Lopinavir reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; EC50s = 26.63 and 26.10 μM, respectively). It reduces lung and kidney viral load, bronchointerstitial pneumonia, and pulmonary inflammatory cell infiltration in a marmoset model of Middle East respiratory syndrome coronavirus (MERS-CoV) infection when administered in combination with ritonavir . | | Uses | A labelled selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product. |
| | Lopinavir-d8 Preparation Products And Raw materials |
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