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| | 5,6,8,14-Tetradehydro-6-methoxy-17-methyl-2,3-[methylenebisoxy]morphinan-7β-ol Basic information |
| Product Name: | 5,6,8,14-Tetradehydro-6-methoxy-17-methyl-2,3-[methylenebisoxy]morphinan-7β-ol | | Synonyms: | 5,6,8,14-Tetradehydro-6-methoxy-17-methyl-2,3-[methylenebisoxy]morphinan-7β-ol;Amurinol I;Nudaurine;Morphinan-7-ol, 5,6,8,14-tetradehydro-6-methoxy-17-methyl-2,3-[methylenebis(oxy)]-, (7β)- (9CI) | | CAS: | 4850-04-8 | | MF: | C19H21NO4 | | MW: | 327.37 | | EINECS: | | | Product Categories: | | | Mol File: | 4850-04-8.mol | ![5,6,8,14-Tetradehydro-6-methoxy-17-methyl-2,3-[methylenebisoxy]morphinan-7β-ol Structure](CAS/20180808/GIF/4850-04-8.gif) |
| | 5,6,8,14-Tetradehydro-6-methoxy-17-methyl-2,3-[methylenebisoxy]morphinan-7β-ol Chemical Properties |
| Melting point | 201-2°C | | Boiling point | 523.6±50.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | pka | 12.41±0.40(Predicted) |
| | 5,6,8,14-Tetradehydro-6-methoxy-17-methyl-2,3-[methylenebisoxy]morphinan-7β-ol Usage And Synthesis |
| Description | A morphine type alkaloid, this base is a minor constituent of the seeds of
Papaver nudicaule var. amurense. It forms clusters of colourless crystals from
Me2CO and has [α] 22
D - 52° (c 1.0, CHCI3). The salts are crystalline and include
the hydriodide, m.p. 198°C (dec.); perchlorate, m.p. 188°C (dec.) and the
picrate, m.p. 150°C (dec.). The structure given above has been determined on the
basis of the infrared, NMR and mass spectra. | | References | Boit, Flentje., Naturwiss., 47,180 (1960)
Flentje, Dopke, Jeffs., ibid, 52,259 (1965)
Dopke, Flentje, Jeffs., Tetrahedron, 24,4459 (1968)
Absolute configuration:
Barton et ai., Chern. Ber., 100,2457 (1967)
Circular dichroism:
Snatzke, Wollenberg.,!. Chern. Soc., C, 1581 (1966) |
| | 5,6,8,14-Tetradehydro-6-methoxy-17-methyl-2,3-[methylenebisoxy]morphinan-7β-ol Preparation Products And Raw materials |
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