| Company Name: |
Chemsky（shanghai）International Co.,Ltd.
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| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester
Purity:98% Package:1820RMB/1Mg; 11200RMB/10Mg
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| Company Name: |
Toronto Research Chemicals
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| Tel: |
+1 (416) 665-9696 |
| Email: |
info@trc-canada.com |
| Products Intro: |
Package:140USD/1mg;1120USD/10mg
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| | Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester Basic information |
| | Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester Chemical Properties |
| solubility | Chloroform, Dichloromethane, DMSO, Methanol | | form | Solid | | color | Off-White |
| | Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. | | Uses | An intermediate in the preparation of Abacavir metabolites |
| | Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester Preparation Products And Raw materials |
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