- NEBULARINE
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- $7.00 / 1KG
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2019-09-02
- CAS: 550-33-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: JD 557
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| | NEBULARINE Basic information |
| | NEBULARINE Chemical Properties |
| Melting point | 181-182°C | | alpha | D25 -48.6° (H2O) | | Boiling point | 395.4°C (rough estimate) | | density | 1.3402 (rough estimate) | | refractive index | 1.6500 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Ethanol, Methanol (Slightly) | | pka | 13.13±0.70(Predicted) | | form | Solid | | color | Pale Beige to Beige | | Merck | 13,6461 | | Stability: | Hygroscopic |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | RTECS | UO9100000 | | Toxicity | LD50 in rats, guinea pigs (mg/kg): 220, 15 s.c. (Truant, D'Amato) |
| | NEBULARINE Usage And Synthesis |
| Description | This purine base is produced by Agarius nebularis Batsch. (Syn. Clitocybe
nebularis). It is laevorotatory with [α]25D - 48.6° (c 1.0, H20). | | Chemical Properties | Crystalline Solid | | Uses | Nebularine is shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria. | | Definition | ChEBI: A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage. | | storage | +4°C | | Purification Methods | Nebularine is recrystallised from butanone/MeOH or EtOH and forms a MeOH photo-adduct. It is a strong inhibitor of adenosine deaminase [EC 3.5.4.4]. [Nair & Weichert Bioorg Chem 9 423 1980, Lfgren et al. Acta Chem Scand 7 225 1953, UV: Brown & Weliky J Biol Chem 204 1019 1953, Beilstein 26 III/IV 1740.] |
| | NEBULARINE Preparation Products And Raw materials |
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