- Z-(2R,3S)-AHPA
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- $1.00 / 1KG
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2019-07-06
- CAS:59969-65-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20kg
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| | (2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Basic information |
| Product Name: | (2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid | | Synonyms: | (2R,3S)-3-(((benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid;Z-(2R,3S)-AHPA;(alphaS,betaR)-alpha-Hydroxy-beta-[[(phenylmethoxy)carbonyl]amino]benzenebutanoic acid;Z-(2S,3R)-AHPA;2S,3R)-3-(((benzyloxy)carbonyl)-Amino)-2-hydroxy-4-phenylbutyric acid;Benzenebutanoic acid, α-hydroxy-β-[[(phenylmethoxy)carbonyl]amino]-, (αS,βR)-;(2S,3R)-3-(((benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid;(2S,3R)-3-(Cbz-amino)-2-hydroxy-4-phenylbutanoic Acid | | CAS: | 59969-65-2 | | MF: | C18H19NO5 | | MW: | 329.35 | | EINECS: | | | Product Categories: | | | Mol File: | 59969-65-2.mol |  |
| | (2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Chemical Properties |
| Melting point | 152-153 °C | | Boiling point | 581.9±50.0 °C(Predicted) | | density | 1.295±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 3.56±0.17(Predicted) |
| | (2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Usage And Synthesis |
| Biological Activity | (2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid (AHPA) derivatives are used as inhibitors of enkephalinase(s) to augment met5-enkephalin-induced anti-nociception. The derivative (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl-L-valine (AHPA-Val) is used as a bestatin analogue. | | Synthesis | (2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid is prepared by Hydrogenolysis of Methyl (αS,βR)-α-hydroxy-β-[[(phenylmethoxy)carbonyl]amino]benzenebutanoate with Sodium hydroxide in 1,4-Dioxane. |
| | (2S,3R)-3-(((Benzyloxy)carbonyl)aMino)-2-hydroxy-4-phenylbutanoic acid Preparation Products And Raw materials |
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