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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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Product Name:Tandospirone Impurity Ⅰ CAS:87721-89-9 Purity:99% HPLC Package:10mg;25mg;50mg;100mg
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Shanghai Kewel Chemical Co., Ltd.
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Product Name:Tandospirone Impurity Ⅰ CAS:87721-89-9 Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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Shanghai Changyan Chem & Tech Co., Ltd.
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Product Name:(3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione CAS:87721-89-9 Purity:95% HPLC Package:5KG;1KG;500G;100G;50G
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Shenzhen ruikai de biotechnology co., ltd.
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Product Name:Tandospirone Impurity 22 CAS:87721-89-9 Purity:98%HPLC Package:10mg;25mg;50mg;100mg
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| (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Basic information |
Product Name: | (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione | Synonyms: | (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione;Tandospirone impurity Ⅰ;Tandospirone Impurity 1;Tandospirone Impurity 22;Tandospirone Impurity 19;4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aR,4R,7S,7aS)-rel- | CAS: | 87721-89-9 | MF: | C21H29N5O2 | MW: | 383.49 | EINECS: | | Product Categories: | | Mol File: | 87721-89-9.mol | |
| (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Chemical Properties |
Boiling point | 613.9±65.0 °C(Predicted) | density | 1.239±0.06 g/cm3(Predicted) | pka | 7.71±0.10(Predicted) |
| (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Usage And Synthesis |
Uses | endo-Tandospirone is an isomer of Tandospirone, which is a selective anxiolytic agent, an anxiety inhibitor. Tandospirone is compared to Buspirone and Diazepam, other anxiolytic agents, and it is suggested that Tandospirone has more anxiolytic activity and anxio-selectivity than the former agents. |
| (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Preparation Products And Raw materials |
Raw materials | 4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-(4-bromobutyl)hexahydro-, (3aR,4R,7S,7aS)-rel--->1-Piperazinebutanenitrile, 4-(2-pyrimidinyl)--->NORBORNANE-2EXO,3EXO-DICARBOXYLIC ACID-ANHYDRIDE-->1-(2-Pyrimidinyl)-4-(4-aminobutyl)piperazine-->CIS-5-NORBORNENE-EXO-2,3-DICARBOXYLIC ANHYDRIDE-->2-(1-Piperazinyl)pyrimidine |
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