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Postion:Product Catalog >API>Specialty drugs>Dermatology drugs> Cesium chloride
Cesium chloride
  • Cesium chloride
  • Cesium chloride

Cesium chloride NEW

Price $6 $5 $1
Package 1KG 25KG 100KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-03-29

Product Details

Product Name: Cesium chloride CAS No.: 7647-17-8
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/03/29
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer
Name: Sun

1. Product information

Names

Namecaesium chloride
SynonymMore Synonyms

 Cesium chloride Biological Activity

DescriptionCesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na+ transport produced by Alloxan[1][2]. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models[3].
Related Catalog
Research Areas >> Cardiovascular Disease
Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
In VitroCesium chloride (CsCl) decreases the increment of membrane potential, the elevation of intracellular calcium and the upregulation of NOS, ET-1 and VEGF expressions, which are induced by Acrolein[3].
In VivoCesium Chloride (12 mg/100 g body weight, daily for 30 days; i.p.; male Wistar rats- BOO model) could significantly weaken the effect of XJT (traditional Chinese medicine) on not only the expression of these potassium channels but also the bladder weight, urodynamics, and oxidative stress[1].
References

[1]. Sun J, Shen W, et al. A Chinese Medicine Formula "Xian-Jia-Tang" for Treating Bladder Outlet Obstruction by Improving Urodynamics and Inhibiting Oxidative Stress through Potassium Channels. Evid Based Complement Alternat Med. 2017;2017:8147258.

[2]. Soto C, et al. Alloxan decreases intracellular potassium content of the isolated frog skin epithelium. Comp Biochem Physiol C Toxicol Pharmacol. 2001;130(1):19-27.

[3]. Ouyang JS, Li YP, Li CY, et al. Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. Free Radic Res. 2012;46(12):1437-1445.

[4]. O'Brien CE, et al. Cesium-induced QT-interval prolongation in an adolescent. Pharmacotherapy. 2008;28(8):1059-1065.

 Chemical & Physical Properties

Density3.983
Boiling Point1290 °C
Melting Point645 °C(lit.)
Molecular FormulaCsCl
Molecular Weight168.359
Flash Point1303°C
Exact Mass167.874298
Index of Refraction1.6418
StabilityStable. Deliquescent. Incompatible with strong oxidizing agents, strong acids. Protect from moisture.
Water Solubility1860 g/L (20 ºC)

 MSDS

Cesium chloride MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • FK9625000

  • CHEMICAL NAME :

  • Cesium chloride

  • CAS REGISTRY NUMBER :

  • 7647-17-8

  • LAST UPDATED :

  • 199701

  • DATA ITEMS CITED :

  • 15

  • MOLECULAR FORMULA :

  • Cl-Cs

  • MOLECULAR WEIGHT :

  • 168.36

  • WISWESSER LINE NOTATION :

  • CS G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 2600 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intraperitoneal

  • SPECIES OBSERVED :

  • Rodent - rat

  • DOSE/DURATION :

  • 1500 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 2306 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intraperitoneal

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 1460 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 910 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LDLo - Lowest published lethal dose

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - rabbit

  • DOSE/DURATION :

  • 1 gm/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 706 mg/kg

  • SEX/DURATION :

  • female 1-21 day(s) pre-mating lactating female 21 day(s) post-birth

  • TOXIC EFFECTS :

  • Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - biochemical and metabolic Reproductive - Effects on Newborn - physical

  • TYPE OF TEST :

  • TDLo - Lowest published toxic dose

  • ROUTE OF EXPOSURE :

  • Oral

  • DOSE :

  • 262 gm/kg

  • SEX/DURATION :

  • female 1-21 day(s) after conception lactating female 21 day(s) post-birth

  • TOXIC EFFECTS :

  • Reproductive - Effects on Newborn - biochemical and metabolic Reproductive - Effects on Newborn - physical

  • TYPE OF TEST :

  • Mutation test systems - not otherwise specified

MUTATION DATA

  • TEST SYSTEM :

  • Rodent - mouse

  • DOSE/DURATION :

  • 125 mg/kg

  • REFERENCE :

  • MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 244,295,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3874 No. of Facilities: 189 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 3353 (estimated) No. of Female Employees: 1792 (estimated)

 Safety Information

SymbolArticle illustration
GHS08
Signal WordWarning
Hazard StatementsH361
Precautionary StatementsP280
Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXn:Harmful
Risk PhrasesR68
Safety PhrasesS36/37-S26
RIDADR2923
WGK Germany2
RTECSFK9625000
HS Code28273980

 Customs

HS Code28273980



2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address : Sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137





Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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Henan Fengda Chemical Co., Ltd

1YR ChinaChina
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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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