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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Quinolones>Gemifioxacin mesylate
Gemifioxacin mesylate
  • Gemifioxacin mesylate
  • Gemifioxacin mesylate
  • Gemifioxacin mesylate
  • Gemifioxacin mesylate
  • Gemifioxacin mesylate

Gemifioxacin mesylate NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-08-18

Product Details

Product Name: Gemifioxacin mesylate CAS No.: 210353-53-0
EC-No.: 1312995-182-4 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/08/18

CAS:210353-53-0
MF:C19H24FN5O7S
MW:485.49
EINECS:1312995-182-4
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:210353-53-0.mol
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Gemifioxacin mesylate Chemical Properties
Melting point 235-2370C
storage temp. room temp
solubility DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form powder
color white to light brown
Stability:Hygroscopic
CAS DataBase Reference210353-53-0(CAS DataBase Reference)
Gemifioxacin mesylate Usage And Synthesis
DescriptionGemifloxacin is a new fluoroquinolone derivative that is active against both Grampositive and Gram-negative bacteria, and it was launched as an oral treatment for bacterial respiratory infections. Compared with other fluoroquinolones currently on the market, gemifloxacin possesses enhanced in vitro activity against Streptococcus pneumoniae, including isolates resistant to b-lactams, macrolides, and ciprofloxacin. Gemifloxacin is specifically indicated for treating community- acquired pneumonia (CAP) caused by multi-drug resistant S. pneumoniae and for treating acute bacterial exacerbations of chronic bronchitis (AECB). The recommended dose of gemifloxacin is 320 mg daily for 5 days for AECB and 320 mg daily for 7 days for CAP.
Chemical Propertiesgemifloxacin mesylate is a synthetic broad-spectrum antibacterial agent for oral administration. Gemifloxacin, a compound related to the fluoroquinolone class of antibiotics, is available as the mesylate salt in the sesquihydrate form. The mesylate salt is a white to light brown solid with a molecular weight of 485.49. Gemifloxacin is considered freely soluble at neutral pH (350 μg/mL at 37oC, pH 7.0).
OriginatorLG Life Sciences (S. Korea)
UsesThird generation fluorinated quinolone antibacterial.
DefinitionChEBI: Gemifloxacin mesylate is the mesylate salt of gemifloxacin. It has a role as an antimicrobial agent and a topoisomerase IV inhibitor. It contains a gemifloxacin.
Brand nameFactive
Biochem/physiol ActionsGemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.

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Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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