Manufacturer Provide Raw Material API CAS 936563-96-1 Ibrutinib Powder

Introduction

Product Name: Ibrutinib 

Other Name :1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one

CAS NO:936563-96-1

Purity: 99%min
Appearance:White crystalline powder

Molecular formula:C25H24N6O2

MW:440.5

Melting Pint :153-158°C

Boiling Point :715.0±60.0 °C(Predicted)

Density:1.34

Storage :Keep in dark place,Inert atmosphere,Room temperature

Ibrutinib (Imbruvica) is a small molecule drug that binds permanently to a protein, Bruton's tyrosine kinase (BTK), that is important in B cells. It is used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia.Vorinostat (Suberoylanilide Hydroxamic Acid, SAHA), it is a hydroxymate HDAC inhibitor that targets class I, II, and IV HDACs. Vorinostat was approved as a therapeutic agent for patients who had undergone at least two systemic therapies for recurrent, progressive, or persistent cutaneous T-cell lymphoma (CTCL).