Picramic acid
Product identifier
- Product name: Picramic acid
- CBnumber: CB1361317
- CAS: 96-91-3
- EINECS Number: 202-544-6
- Synonyms: PICRAMIC ACID,picramic
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Explosives, Division 1.1
Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Acute toxicity - Category 4, Inhalation
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
Label elements
Pictogram(s)
-
Signal word
Danger
H201 Explosive; mass explosion hazard
H302 Harmful if swallowed
H312 Harmful in contact with skin
H332 Harmful if inhaled
H412 Harmful to aquatic life with long lasting effects
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P230 Keep wetted with ...
P234 Keep only in original packaging.
P240 Ground and bond container and receiving equipment.
P250 Do not subject to grinding/shock/friction/….
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P370+P372+P380+P373 In case of fire: Explosion risk. Evacuate area. DO NOT fight fire when fire reaches explosives.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P401 Store in accordance with…
P503 Refer to manufacturer/supplier… for information on disposal/recovery/recycling.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: Picramic acid
- Synonyms: PICRAMIC ACID,picramic
- CAS: 96-91-3
- EC number: 202-544-6
- MF: C6H5N3O5
- MW: 199.12
Description of first aid measures
If inhaledMove the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
SYMPTOMS: Dizziness, abdominal cramps, vomiting, bloody diarrhea, weakness, convulsions and collapse. Small repeated doses may lead to weakness general depression, headache, and mental impairment. ACUTE/CHRONIC HAZARDS: This compound is a fire hazard and should not be subjected to shock or heat. This compound is a local irritant. (NTP, 1992)
Indication of any immediate medical attention and special treatment needed
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary . Monitor for pulmonary edema and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes if immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Cover skin burns with dry sterile dressings after decontamination . Rapid body cooling may be necessary in case of hyperthermia. Salicylates are contraindicated. Dinitrophenol and related compounds
Extinguishing media
Fires involving this chemical can be controlled using dry chemical, CO2, or Halon foam extinguishers. (NTP, 1992)
Specific Hazards Arising from the Chemical
This chemical ignites rapidly and burns relatively fast. (NTP, 1992)
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Information on basic physicochemical properties
- Physical state
Solid. Crystalline.
- Colour
Dark red.
- Odour
no data available
- Melting point/freezing point
169 °C. Remarks:Other details not available.
- Boiling point or initial boiling point and boiling range
375.27 °C. Remarks:Other details not available.
- Flammability
no data available
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
210 °C.
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- Solubility
less than 1 mg/mL at 68.9° F (NTP, 1992)
- Partition coefficient n-octanol/water
log Pow = 0.93. Remarks:Other details not available.
- Vapour pressure
0 Pa. Temperature:25 °C. Remarks:Reported as 0.000000416 mmHg.
- Density and/or relative density
1.749 g/cm 3
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
Highly flammable. Insoluble in water.
Chemical stability
no data available
Possibility of hazardous reactions
IN CONTACT WITH OPEN FLAME IN GLASS TUBE OR BEAKER, IGNITES RAPIDLY & BURNS RELATIVELY FAST...2-AMINO-4,6-DINITROPHENOL should not be subjected to strong shock or heat, and is a dangerous fire risk. This compound reacts with strong oxidizing agents. (NTP, 1992). Explodes if dried and exposed to heat, flame, friction or shock. Wetting greatly reduces this tendency. Treat as an explosive. Mixing with reducing agents, including hydrides, sulfides, nitrides, and alkali metals may lead to a vigorous reaction that culminates in a detonation. May explode in the presence of a base such as sodium hydroxide or potassium hydroxide, even in the presence of water or organic solvents. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. An amino acid (reacts as an acid with bases and as a base with acids).
Conditions to avoid
no data available
Incompatible materials
Combustible when exposed to ... oxidizers.
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of nitroxides.
Acute toxicity
- Oral: LD50 - rat (male/female) - 110 mg/kg bw.
- Inhalation: no data available
- Dermal: LD50 - rabbit (male/female) - > 5 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
Toxicity
- Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 46.2 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 7.371 mg/L - 48 h.
- Toxicity to algae: EC50 - microalgae - 10.45 mg/L - 72 h.
- Toxicity to microorganisms: IC50 - Tetrahymena pyriformis - 52.2 mg/L - 48 h.
Persistence and degradability
no data available
Bioaccumulative potential
A BCF value of 42 was reported for 4,6-dinitro-2-aminophenol in rainbow trout(1). According to a classification scheme(2), this BCF value suggests that bioconcentration in aquatic organisms is moderate.
Mobility in soil
The Koc of 4,6-dinitro-2-aminophenol is estimated as approximately 75(SRC), from its log Kow of 0.93(1) and a regression derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 4,6-dinitro-2-aminophenol is expected to have high mobility in soil.
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN3317 (For reference only, please check.)
IMDG: UN3317 (For reference only, please check.)
IATA: UN3317 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: 2-AMINO-4,6-DINITROPHENOL, WETTED with not less than 20% water, by mass (For reference only, please check.)
IMDG: 2-AMINO-4,6-DINITROPHENOL, WETTED with not less than 20% water, by mass (For reference only, please check.)
IATA: 2-AMINO-4,6-DINITROPHENOL, WETTED with not less than 20% water, by mass (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 4.1 (For reference only, please check.)
IMDG: 4.1 (For reference only, please check.)
IATA: 4.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.