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ChemicalBook >> CAS DataBase List >> ON-01910

ON-01910

ON-01910 price.
  • $34 - $2000
  • Product name: ON-01910
  • CAS: 1225497-78-8
  • MF: C21H26NNaO8S
  • MW: 475.49
  • EINECS:-0
  • MDL Number:MFCD11655911
  • Synonyms:ON-01910;Estybon;N-[2-Methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine sodium salt;ON 01910 sodium salt;ON-01910;ESTYBON;Rigosertib (ON-01910);N-[2-methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-glycine,sodium salt (1:1);N-[2-Methoxy-5-[[[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine sodium salt Rigosertib (ON-01910)
15 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberX7376
  • Product descriptionSodium{[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate
  • Packaging25mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000600
  • Product descriptionON-01910 95.00%
  • Packaging5MG
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1404
  • Product descriptionRigosertibsodiumsalt
  • Packaging10mM(in 1mL DMSO)
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60271
  • Product descriptionRigosertib(ON-01910) ≥98%
  • Packaging10mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15553
  • Product descriptionON-01910 (sodium salt) ≥98%
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15553
  • Product descriptionON-01910 (sodium salt) ≥98%
  • Packaging5mg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15553
  • Product descriptionON-01910 (sodium salt) ≥98%
  • Packaging10mg
  • Price$150
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15553
  • Product descriptionON-01910 (sodium salt) ≥98%
  • Packaging25mg
  • Price$330
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM295047
  • Product descriptionSodium2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl)amino)acetate 95%
  • Packaging50mg
  • Price$409
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004210
  • Product descriptionON-01910.Na 95+%
  • Packaging25mg
  • Price$242
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004210
  • Product descriptionON-01910.Na 95+%
  • Packaging50mg
  • Price$411
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7265
  • Product descriptionRigosertib >98%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7265
  • Product descriptionRigosertib >98%
  • Packaging250mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7265
  • Product descriptionRigosertib >98%
  • Packaging1g
  • Price$2000
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberO657000
  • Product descriptionON-01910SodiumSalt
  • Packaging25mg
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7376 Sodium{[2-methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]amino}acetate 25mg $420 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000600 ON-01910 95.00% 5MG $330 2021-12-16 Buy
ApexBio Technology A1404 Rigosertibsodiumsalt 10mM(in 1mL DMSO) $220 2021-12-16 Buy
Arctom CFN60271 Rigosertib(ON-01910) ≥98% 10mg $238 2021-12-16 Buy
Cayman Chemical 15553 ON-01910 (sodium salt) ≥98% 1mg $34 2024-03-01 Buy
Cayman Chemical 15553 ON-01910 (sodium salt) ≥98% 5mg $85 2024-03-01 Buy
Cayman Chemical 15553 ON-01910 (sodium salt) ≥98% 10mg $150 2024-03-01 Buy
Cayman Chemical 15553 ON-01910 (sodium salt) ≥98% 25mg $330 2024-03-01 Buy
Chemenu CM295047 Sodium2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl)amino)acetate 95% 50mg $409 2021-12-16 Buy
Crysdot CD31004210 ON-01910.Na 95+% 25mg $242 2021-12-16 Buy
Crysdot CD31004210 ON-01910.Na 95+% 50mg $411 2021-12-16 Buy
DC Chemicals DC7265 Rigosertib >98% 100mg $500 2021-12-16 Buy
DC Chemicals DC7265 Rigosertib >98% 250mg $1000 2021-12-16 Buy
DC Chemicals DC7265 Rigosertib >98% 1g $2000 2021-12-16 Buy
TRC O657000 ON-01910SodiumSalt 25mg $250 2021-12-16 Buy

Properties

Melting point :>256oC (dec.)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :Pale Yellow to Pale Green

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ON-01910 is a potent, non-ATP-competitive inhibitor of polo-like kinase 1 (Plk1; IC50 = 9 nM), a serine/threonine protein kinase involved in the regulation of cell cycling. It induces apoptosis in a wide array of tumor cell lines (GI50 = 50-200 nM) and blocks the growth of multidrug resistant cancer cell lines. ON-01910 is active in vivo when administered intraperitoneally and synergizes with chemotherapeutic agents, preventing tumor growth or abolishing tumors in human xenograft nude mouse models.

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