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1,3,5(10)-estratriene synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: aq. CrO3 / acetone
2: N2H4*H2O, KOH / bis-(2-hydroxy-ethyl) ether / 195 °C

References:

Cherkasov,A.N. et al. [Journal of Organic Chemistry USSR (English Translation),1974,vol. 10,p. 321 - 328][Zhurnal Organicheskoi Khimii,1974,vol. 10,p. 320 - 328]