1,6-DIPHENYL-1,5-HEXADIENE-3,4-DIOL synthesis
- Product Name:1,6-DIPHENYL-1,5-HEXADIENE-3,4-DIOL
- CAS Number:4403-20-7
- Molecular formula:C18H18O2
- Molecular Weight:266.33
104-55-2
639 suppliers
$6.00/25g
4403-20-7
10 suppliers
$130.00/1g
Yield:4403-20-7 67%
Reaction Conditions:
with triethylammonium formate;magnesium in methanol;water at 25; for 0.5 h;
Steps:
General procedure for the rapid pinacolization
General procedure: To a vigorously stirred suspension of triethylammonium formate (15 mmol), aromatic aldehyde/arylmethylketone (10 mmol) in aqueousmethanol (5 ml-) wasadded followed bymagnesium turnings (10 mmol). After thecompletion of the reaction, the reaction mixture was filtered and the residue was washed withwater, ethyl acetate (2 x 10 ml). The filtrate wasdiluted with water (25 ml) and repeatedly extractedwith ethyl acetate (3 x 15 ml). The combinedorganic extracts and washings were washed with water(2x 10 ml), dried over anhydrous sodium sulfate. Solvent removal under reduced pressure gave a white solid, which was further purified by recrystallization using dichloromethane andlight petroleum (40-60°C) to get pinacol as whitesolid.
References:
Pamar, M. Geeta;Govender;Muthusamy;Krause, Ruiw M.;Nanjundaswamy [Oriental Journal of Chemistry,2013,vol. 29,# 3,p. 969 - 974]
104-55-2
639 suppliers
$6.00/25g
104-54-1
621 suppliers
$13.00/25g
4403-20-7
10 suppliers
$130.00/1g
104-55-2
639 suppliers
$6.00/25g
4403-20-7
10 suppliers
$130.00/1g
4407-36-7
72 suppliers
$19.00/25g
