ChemicalBook CAS DataBase List 4-(Naphthalene-1-yl)phenylboronic acid pinacol ester

4-(Naphthalene-1-yl)phenylboronic acid pinacol ester synthesis

8synthesis methods

Product Name:4-(Naphthalene-1-yl)phenylboronic acid pinacol ester
CAS Number:1028729-05-6
Molecular formula:C22H23BO2
Molecular Weight:330.23

24382-97-6
15 suppliers
$504.00/250mg

73183-34-3
556 suppliers
$6.00/5g

4-(Naphthalene-1-yl)phenylboronic acid pinacol ester

1028729-05-6
35 suppliers
inquiry

Yield:1028729-05-6 78%

Reaction Conditions:

with potassium acetate;bis(dibenzylideneacetone)-palladium⁽⁰⁾;tricyclohexylphosphine in 1,4-dioxane;Reflux;

Steps:

1.20 20) Preparation of Compound C-6

13 g (54.46 mmol, 1 eq) of Compound C-5 and 21 g (81.69 mmol, 1.5 eq) of bis(pinacolato)diboron, Pd(dba)2 1.5g (2.72mmol, 0.05eq), PCy3 1.5g (5.44 mmol, 0.1eq) and 21 g of KOAc (217.83 mmol, 4eq) were added, and 300 ml of 1,4-dioxane was added and stirred under reflux. After the reaction was completed, the mixture was extracted with CH2Cl2/H2O and CH2Cl2 layer was dried with MgSO4. Silica-gel column purification to give 14g of compound C-6 in 78% yield.

References:

KR102019923,2019,B1 Location in patent:Paragraph 0209-0213

61676-62-8 Synthesis