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2-(3-BUTENYL)BENZOIC ACID synthesis

5synthesis methods
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Yield:89730-30-3 98%

Reaction Conditions:

Stage #1: ortho-methylbenzoic acidwith lithium diisopropyl amide in tetrahydrofuran;n-heptane;ethylbenzene at 0; for 3 h;Inert atmosphere;
Stage #2: allyl bromide in tetrahydrofuran;n-heptane;ethylbenzene at 0 - 20;Inert atmosphere;

References:

Chen, Hui;Jin, Weiwei;Yu, Shouyun [Organic Letters,2020,vol. 22,# 15,p. 5910 - 5914] Location in patent:supporting information