ChemicalBook CAS DataBase List 2,4,6-Tribromoaniline

2,4,6-Tribromoaniline synthesis

14synthesis methods

Product Name:2,4,6-Tribromoaniline
CAS Number:147-82-0
Molecular formula:C6H4Br3N
Molecular Weight:329.81

2,4,6-Tribromoaniline can be prepared by treating bromine water with aniline in a solution of acetic acid or dilute hydrochloric acid:
synthesis of 2,4,6-Tribromoaniline

synthesis-of-2-4-6-tribromoaniline-from-aniline

615-36-1
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147-82-0
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Yield:147-82-0 90%

Reaction Conditions:

with dibromamine-T in acetonitrile at 20; for 0.166667 h;

Steps:

2, 4, 6-Tribromoaniline
General procedure: TsNBr2 (1 mmol) was added at 0 C to a solution of the aromatic compound(1 mmol) in acetonitrile (2 mL). After 10 min of stirring at room temperature, sodium thiosulfate (200 mg approx.) was added and stirred for 10 min. The reaction wastaken up in ethyl acetate, dried over NaSO4, and concentrated. The crude productwas purified by flash chromatography or silica gel (230-400 mesh) with a mixtureof petroleum ether and ethyl acetate as eluent.

References:

Saikia, Indranirekha;Chakraborty, Pranita;Sarma, Manas Jyoti;Goswami, Mridusmita;Phukan, Prodeep [Synthetic Communications,2015,vol. 45,# 2,p. 211 - 217]

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106-40-1 Synthesis