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ChemicalBook CAS DataBase List 2-Chloro-N4-(2-methypropyl)-3,4-quinolinediamine

2-Chloro-N4-(2-methypropyl)-3,4-quinolinediamine synthesis

5synthesis methods
2,4-DICHLORO-3-NITRO-QUINOLINE

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2-Chloro-N4-(2-methypropyl)-3,4-quinolinediamine

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-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 17.8 g / Et3N / CH2Cl2 / 0.5 h / Heating
2: H2; MgSO4 / Pt/C / ethyl acetate / 2585.74 Torr

References:

Gerster, John F.;Lindstrom, Kyle J.;Miller, Richard L.;Tomai, Mark A.;Birmachu, Woubalem;Bomersine, Shannon N.;Gibson, Shiela J.;Imbertson, Linda M.;Jacobson, Joel R.;Knafla, Roy T.;Maye, Peter V.;Nikolaides, Nickolas;Oneyemi, Folakemi Y.;Parkhurst, Gwen J.;Pecore, Sharon E.;Reiter, Michael J.;Scribner, Lisa S.;Testerman, Tracy L.;Thompson, Natalie J.;Wagner, Tammy L.;Weeks, Charles E.;Andre, Jean-Denis;Lagain, Daniel;Bastard, Yvon;Lupu, Michel [Journal of Medicinal Chemistry,2005,vol. 48,# 10,p. 3481 - 3491]

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