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(2R,4R)-4-Hydroxy-2-pyrrolidinemethanol synthesis

4synthesis methods
(2R,4R)-4-Hydroxy-2-pyrrolidinemethanol

343633-22-7
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Yield:343633-22-7 98%

Reaction Conditions:

with 10% Pd on charcoal;hydrogen in methanol;ethyl acetate at 20; under 517.162 Torr; for 12 h;Inert atmosphere;

References:

Vaněk, Václav;Budě?ínsky, Milo?;Rinnová, Markéta;Rosenberg, Ivan [Tetrahedron,2009,vol. 65,# 4,p. 862 - 876] Location in patent:experimental part