3-Dimethylaminophenol synthesis
- Product Name:3-Dimethylaminophenol
- CAS Number:99-07-0
- Molecular formula:C8H11NO
- Molecular Weight:137.18
124-40-3
499 suppliers
$18.00/100ml
108-46-3
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$10.00/10g
99-07-0
304 suppliers
$9.00/5g
Yield:99-07-0 93%
Reaction Conditions:
with hydrogen in water at 200; under 375.038 Torr; for 3 h;Autoclave;Reagent/catalyst;
Steps:
2. Experimental section
General procedure: General procedure for the amination of resorcinol with secondaryamine catalyzed by Raney Ni. Resorcinol (2.2 g, 20 mmol), secondaryamine (30 mmol) and Raney Ni (110 mg) were added to water(50 ml) in a 100 ml autoclave. The autoclave was purged with hydrogengas three times, then maintained 0.05 Mpa pressure. The mixturewas heated to 200 °C rapidly. Then stirring was maintained for 3 h.The reaction mixture was cooled to room temperature, and then extractedwith N-butyl acetate. The organic layer was dried (MgSO4), filteredand concentrated to give the crude product. The pure productwas got through flash column chromatography on silica gel (petroleumether/acetylacetic ester (3/1, v/v)).
References:
Ge, Xin;Pan, Jiong-Bin;Qian, Chao;Feng, Lie;Chen, Yun-Bin;Chen, Xin-Zhi [Catalysis Communications,2014,vol. 46,p. 201 - 207]
15799-79-8
99 suppliers
$18.00/5g
99-07-0
304 suppliers
$9.00/5g
