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3-OXO-3-(4-PHENYL-PIPERAZIN-1-YL)-PROPIONITRILE synthesis

4synthesis methods
1-Piperazinepropanamide, β-oxo-4-phenyl-

1193366-16-3
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Yield:14761-40-1 90%

Reaction Conditions:

with pyridine;p-toluenesulfonyl chloride at 15 - 20;

References:

Manikowski, Andrzej;Kolarska, Zofia [Synthetic Communications,2009,vol. 39,# 20,p. 3621 - 3638] Location in patent:experimental part