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6-BROMOQUINOLINE-2-CHLORO-3-CARBONITRILE synthesis

4synthesis methods
99465-03-9 Synthesis
6-Bromo-2-oxo-1,2-dihydro-3-quinolinecarbonitrile

99465-03-9
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Yield:99465-04-0 52%

Reaction Conditions:

with trichlorophosphate for 1.5 h;Heating;

References:

Alabaster;Bell;Campbell;Ellis;Henderson;Roberts;Ruddock;Samuels;Stefaniak [Journal of Medicinal Chemistry,1988,vol. 31,# 10,p. 2048 - 2056]